Which atypical antipsychotic?

Patients on Atypical Antipsychotic Drugs

Patients with schizophrenia are more likely than the general population to develop diabetes, which contributes to a high risk of cardiovascular complications; individuals with schizophrenia are two to three times more likely to die from cardiovascular disease than the general population. The risk of diabetes, and hence cardiovascular disease, is particularly increased by some of the new atypica...

What makes an antipsychotic atypical?

YKP1447, A Novel Potential Atypical Antipsychotic Agent.

(S)-Carbamic acid 2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-1-phenyl-ethyl ester hydrochloride (YKP1447) is a novel "atypical" antipsychotic drug which selectively binds to serotonin (5-HT(2A), Ki=0.61 nM, 5-HT(2C), Ki=20.7 nM) and dopamine (D(2), Ki=45.9 nM, D(3), Ki=42.1 nM) receptors with over 10~100-fold selectivity over the various receptors which exist in the brain. In the behavioral studie...

Atypical antipsychotic induced obsessive-compulsive symptoms.

Recently, we came across an interesting case where Mr. A, a 26 year old Malay man with resistant schizophrenia, paranoid subtype, developed atypical antipsychotic induced obsessive-compulsive symptoms. Various attempts to treat him with conventional antipsychotics and risperidone had failed because he developed intolerable extrapyramidal side effects. Hence, he was started on clozapine. His psy...

Newer oral atypical antipsychotic agents: a review.

“black-box” warnings for all antipsychotic drugs.2 Antipsychotic agents may be classified in several ways. Commonly, they can be designated as older drugs (often called conventional or “typical” antipsychotics) and newer “atypicals.” The term atypical refers to the perceived lower likelihood of extrapyramidal symptoms, a sequela that had been deemed characteristic of the first generation of ant...